Quel que sont les options binaire
The efficacy of IV metronidazole has not been definitively demonstrated, but at least one retrospective study examined its use as monotherapy in 10 patients with CDAD. 17 A majority of these patients experienced resolution, and none developed fulminant colitis or toxicity such as peripheral neuropathy. Another adjunctive therapy is the rectal administration of vancomycin. Although 5 of the patients received surgical consultation, none of the patients required colectomy, and 8 of the 9 patients achieved clinical cure.
The interval of administration varied among patients and ranged from 4 to 12 hours.